| Name | Class | C. | Type | Resources | Traits | Pack | Set |
|---|---|---|---|---|---|---|---|
| SP//dr Suit | Hero | Hero | Active. Web-Warrior. | SP//dr 1 | SP//dr | ||
| VEN#m: Addy Brock | Hero | 4 | Ally | SP//dr 3 | SP//dr 3 | ||
| All Systems Go! | Hero | 1 | Event | SP//dr 4 | SP//dr 4-6 | ||
| Rapid Deployment | Hero | 2 | Event | Thwart. | SP//dr 5 | SP//dr 7-8 | |
| Web-Trap | Hero | 2 | Event | Attack. | SP//dr 6 | SP//dr 9-10 | |
| Aunt May & Uncle Ben | Hero | 1 | Support | Persona. | SP//dr 7 | SP//dr 11 | |
| Ejection Protocol | Hero | 0 | Support | Tactic. | SP//dr 8 | SP//dr 12 | |
| SP//dr Command | Hero | 1 | Support | Location. | SP//dr 9 | SP//dr 13 | |
| Host Spider | Hero | 3 | Upgrade | Interface. Spider. | SP//dr 10 | SP//dr 14 | |
| Psychic Link | Hero | 2 | Upgrade | Interface. Tech. | SP//dr 11 | SP//dr 15 | |
| Speed-Metal Alloy | Hero | 1 | Upgrade | Interface. Tech. | SP//dr 12 | SP//dr 16 | |
| Web-Fluid Compressor | Hero | 2 | Upgrade | Interface. Tech. | SP//dr 13 | SP//dr 17 | |
| Daredevil | Protection | 2 | Ally | SP//dr 14 | |||
| Spider-Man Noir | Protection | 3 | Ally | Web-Warrior. | SP//dr 15 | ||
| Repurpose | Protection | 0 | Event | Skill. | SP//dr 16 | ||
| Thwip! Thwip! | Protection | 2 | Event | Superpower. | SP//dr 17 | ||
| Energy Barrier | Protection | 2 | Upgrade | Item. Tech. | SP//dr 18 | ||
| Forcefield Generator | Protection | 3 | Upgrade | Tech. | SP//dr 19 | ||
| Spider-Tingle | Protection | 1 | Upgrade | Superpower. | SP//dr 20 | ||
| Spider-Ham: Peter Porker | Basic | 3 | Ally | Cartoon. Web-Warrior. | SP//dr 21 | ||
| Spider-Man: Otto Octavius | Basic | 2 | Ally | Web-Warrior. | SP//dr 22 | ||
| Limitless Stamina | Basic | 1 | Event | Superpower. | SP//dr 23 | ||
| Unshakable | Basic | 1 | Upgrade | Condition. Superpower. | SP//dr 24 | ||
| Inherited Burden | Encounter | Obligation | SP//dr 25 | SP//dr | |||
| Giant Monster Attack | Encounter | Side Scheme | SP//dr 26 | SP//dr Nemesis 1 | |||
| M.O.R.B.I.U.S. | Encounter | Minion | Creature. | SP//dr 27 | SP//dr Nemesis 2 | ||
| Energy Drain | Encounter | Treachery | SP//dr 28 | SP//dr Nemesis 3-5 | |||
| Clarity of Purpose | Leadership | 1 | Upgrade | Condition. | SP//dr 29 | ||
| Grand Larceny | Encounter | Side Scheme | SP//dr 30 | Iron Spider's Sinister Six 1 | |||
| Bombshell | Encounter | Minion | Criminal. | SP//dr 31 | Iron Spider's Sinister Six 2 | ||
| Electro | Encounter | Minion | Criminal. | SP//dr 32 | Iron Spider's Sinister Six 3 | ||
| Hobgoblin | Encounter | Minion | Criminal. | SP//dr 33 | Iron Spider's Sinister Six 4 | ||
| Iron Spider | Encounter | Minion | Criminal. Elite. | SP//dr 34 | Iron Spider's Sinister Six 5 | ||
| Sandman | Encounter | Minion | Criminal. | SP//dr 35 | Iron Spider's Sinister Six 6 | ||
| Spot | Encounter | Minion | Criminal. | SP//dr 36 | Iron Spider's Sinister Six 7 | ||
| Surge in Crime | Encounter | Environment | SP//dr 37 | Iron Spider's Sinister Six 8 |