| Name | Class | C. | Type | Resources | Traits | Pack | Set |
|---|---|---|---|---|---|---|---|
| Defensive Stance | Protection | 2 | Upgrade | Preparation. Tactic. | Black Widow 32 | ||
| Flow Like Water | Protection | 2 | Upgrade | Condition. | Vision 16 | ||
| Forcefield Generator | Protection | 3 | Upgrade | Tech. | SP//dr 19 | ||
| Nerves of Steel | Protection | 2 | Upgrade | Skill. | Quicksilver 17 | ||
| Unflappable | Protection | 1 | Upgrade | Condition. | Doctor Strange 20 | ||
| Unflappable | Protection | 1 | Upgrade | Condition. | Rogue 13 | ||
| Black Widow: Natasha Romanoff | Protection | 3 | Ally | S.H.I.E.L.D. Spy. | Core Set 75 | ||
| Elixir: Josh Foley | Protection | 4 | Ally | X-Force. | Angel 11 | ||
| Iron Fist: Danny Rand | Protection | 4 | Ally | Defender. | Doctor Strange 14 | ||
| Defensive Training | Protection | 1 | Support | Condition. | Nebula 34 | ||
| Defensive Protocols | Campaign | Side Scheme | The Mad Titan's Shadow 184 | The Mad Titan's Shadow Campaign 8 | |||
| Enemy of My Enemy | Campaign | Side Scheme | Mutant Genesis 172 | Mutant Genesis Campaign 2 | |||
| Find the Norn Stones | Campaign | Side Scheme | The Mad Titan's Shadow 186 | The Mad Titan's Shadow Campaign 13 | |||
| Find the Prisoners | Campaign | Side Scheme | Mutant Genesis 173 | Mutant Genesis Campaign 3 | |||
| Frightened Police | Campaign | Side Scheme | Mutant Genesis 171 | Mutant Genesis Campaign 1 | |||
| Hack Sanctuary's Computer | Campaign | Side Scheme | The Mad Titan's Shadow 184 | The Mad Titan's Shadow Campaign 8 | |||
| Magneto's Fortress | Campaign | Side Scheme | Mutant Genesis 175 | Mutant Genesis Campaign 5 | |||
| Off the Rails | Campaign | Side Scheme | Sinister Motives 179 | Community Service 4 | |||
| Surprise Attack | Campaign | Side Scheme | Mutant Genesis 174 | Mutant Genesis Campaign 4 | |||
| Defy Danger | Campaign | 1 | Event | Attack. | Galaxy's Most Wanted 159 | The Market 10 | |
| In Defiance | Campaign | 0 | Event | Galaxy's Most Wanted 153 | The Market 4 | ||
| Safeguard | Campaign | 0 | Event | Galaxy's Most Wanted 168 | The Market 19 | ||
| Take the Fight to Them | Campaign | 0 | Event | Galaxy's Most Wanted 161 | The Market 12 | ||
| Basic Defense Upgrade | Campaign | Upgrade | Condition. | The Rise of Red Skull 161 | Hydra Campaign | ||
| Brazen Defense | Campaign | 0 | Upgrade | Skill. | Mutant Genesis 178 | Brawler 3 | |
| Determined Defense | Campaign | 0 | Upgrade | Skill. | Mutant Genesis 189 | Defender 4 | |
| Ferocious Attack | Campaign | 0 | Upgrade | Skill. | Mutant Genesis 179 | Brawler 4 | |
| Fortitude | Campaign | 0 | Upgrade | Skill. | Mutant Genesis 195 | Peacekeeper 5 | |
| Blink: Clarice Ferguson | Campaign | 4 | Ally | X-Men. | Age of Apocalypse 173 | ||
| Fandral | Campaign | Ally | Asgard. Captive. | The Mad Titan's Shadow 191 | The Mad Titan's Shadow Campaign 21 | ||
| Lady Sif | Campaign | Ally | Asgard. Captive. | The Mad Titan's Shadow 190 | The Mad Titan's Shadow Campaign 20 | ||
| Safehouse | Campaign | 4 | Support | Location. | NeXt Evolution 197 | Next Evolution Campaign 11 | |
| Reactive Defense | Campaign | Obligation | Mutant Genesis 174 | Mutant Genesis Campaign 4 | |||
| Establish Safehouse | Campaign | Player Side Scheme | NeXt Evolution 191 | Next Evolution Campaign 2 | |||
| Prepare Defenses | Campaign | Player Side Scheme | NeXt Evolution 195 | Next Evolution Campaign 6 | |||
| Self Confidence | 'Pool | Resource | Deadpool 25 | ||||
| Self Control | 'Pool | Resource | Deadpool 26 | ||||
| Self Preservation | 'Pool | Resource | Deadpool 27 | ||||
| Get in Front of Me! | 'Pool | 1 | Event | Deadpool 47 | |||
| Healing Factor | 'Pool | 3 | Upgrade | Superpower. | Deadpool 29 | ||
| Bob, Agent of Hydra: Bob Dobalina | 'Pool | 2 | Ally | Hydra. | Deadpool 43 |