Wolverine - Hit me more

Pump up Wolverine's HP to 31 and base REC to 7 (though you're likely to never need to swap to AE). Facetank the hits. "Come Get Me, Bub!" and Taunt for card draw/ toughness. Energy Barrier and Dauntless can ping retaliatory damage.

Get Behind Me! and Stepford Cuckoos are very handy for dealing with those nasty treachery cards.

Rogue can tap Wolverine for +4 attack when he's set up.

Synch is there to boost your defence, recover or attack as needed (and another target for Utopia).

Berserker Frenzy will be doing work; and you should get Front Line Specialist mid to late game for additional card draw.

You're not there to thwart - take the hits for others and use your HP to deal with minions with your events. Start hitting the villain once the board is clear.