As others have pointed out this card works best at amping damage from a single attack with multiple targets. Some examples are given in the other reviews but my favorite is Wasp Giant form. Her basic attacks can be split between enemies by default resulting in each enemy taking additional damage. The ceiling for this can be incredibly high depending on scenario/player count (the more minions the better). This gets particularly fun when combined with Hand Cannon, Rapid Growth, and Follow Through for multiple instances of Overkill damage dumped onto the Villain. This particular combo is niche since it only works with Wasp, but she’s probably the most consistent user of this card.