X-23 stab stab stab

The idea here is to get your ATK value as high as possible so every attack you make does massive damage. Then you ready your hero to do it again. Combat Training, Aggressive Conditioning and Symbiote Suit give you extra damage all the time while Godslayer and Hand Cannon give you ATK up for the villain or minions respectively. Because X-23 is prone to taking a lot of damage there is also a lot of ways to increase her HP in here as well, allowing you to stay on hero side longer.