| Name | Class | C. | Type | Resources | Traits | Pack | Set |
|---|---|---|---|---|---|---|---|
| Mister Sinister (I) | Encounter | Villain | Genius. | NeXt Evolution 136 | Mister Sinister 1 | ||
| Mister Sinister (II) | Encounter | Villain | Genius. | NeXt Evolution 137 | Mister Sinister 2 | ||
| Mister Sinister (III) | Encounter | Villain | Genius. | NeXt Evolution 138 | Mister Sinister 3 | ||
| Sinister Intent | Encounter | Main Scheme | NeXt Evolution 139 | Mister Sinister 4 | |||
| Taking Off | Encounter | Main Scheme | NeXt Evolution 140 | Mister Sinister 5 | |||
| Bulking Up | Encounter | Main Scheme | NeXt Evolution 141 | Mister Sinister 6 | |||
| Focusing In | Encounter | Main Scheme | NeXt Evolution 142 | Mister Sinister 7 | |||
| Sinister Ends | Encounter | Main Scheme | NeXt Evolution 143 | Mister Sinister 8 | |||
| Sinister Disguise | Encounter | Attachment | Condition. | NeXt Evolution 144 | Mister Sinister 9 | ||
| Sinister Soldier | Encounter | Minion | Clone. | NeXt Evolution 145 | Mister Sinister 10-11 | ||
| Teleported Away | Encounter | Side Scheme | NeXt Evolution 146 | Mister Sinister 12 | |||
| Genetic Mastery | Encounter | Treachery | NeXt Evolution 147 | Mister Sinister 13-14 | |||
| Molecular Control | Encounter | Treachery | NeXt Evolution 148 | Mister Sinister 15 | |||
| Sinister Schemes | Encounter | Treachery | NeXt Evolution 149 | Mister Sinister 16 | |||
| Sinister Strike | Encounter | Treachery | NeXt Evolution 150 | Mister Sinister 17 |