Similar to Godlike Stamina for Asgardians, Reboot is so good that it might just be considered an extension of Vision's Signature Pool. He's the only Android Hero with the only Android Signature, and Reboot is amazing on both of these.
While usable on the available Android allies, none of them are particularly worth building around.
Jocasta (Protection) - Not worthwhile to heal her for a single point of damage, and the heal won't cover a 2nd THW.
Machine Man (Basic) - With 1/1 stats, not worth it. It's expensive to boost his stats, and the boost lasts for single activation, not the entire round.
Protector (Protection) - Prohibitively expensive to keep her going, as you have to pay a Mental resource to use her worthwhile power (ATK) with double consequential damage.
Victor Mancha (Protection) - Can't attack or defend, and you can't interrupt during the Villain phase to ready him to defend again.
Ironically, the only Android Ally worth including Reboot for is Vision (Leadership). Reboot could easily turn Vision into an awesome Voltron type. Imagine a Vision with Inspired, Reinforced Suit, and maybe a Skycycle. It might not be the most efficient build, but it would be fun!
Vision (3), Inspired(1), Reinf. Suit (1), Skycycle (1), Reboot x3 (3), 3 boosts (7 cards, 12 resources total)=40 damage. Could add Sidearm (1) for an extra 8 damage.
An S card for Vision: Should always be included, probably x3. Cheap readying and a heal is too powerful to ignore.
For non-Vision Heroes: Likely a C, too niche to be worth while without a very specific build.